منابع مشابه
Congenital absence of pulmonary valve leaflets.
Congenital absence of pulmonary valve leaflets is an uncommon condition usually associated with ventricular septal defect and an obstructive pulmonary valve ring. Twenty-one patients with these malformations are described. Twenty had an associated ventricular septal defect with ventriculoarterial concordance, and one also had transposition of the great arteries, ventricular septal defect, and o...
متن کاملDecellularized tissue-engineered heart valve leaflets with recellularization potential.
Tissue-engineered heart valves (TEHV) have been proposed as a promising solution for the clinical needs of pediatric patients. In vivo studies have shown TEHV leaflet contraction and regurgitation after several months of implantation. This has been attributed to contractile cells utilized to produce the extracellular matrix (ECM) during TEHV culture. Here, we utilized such cells to develop a ma...
متن کاملModeling the mechanics of tissue-engineered human heart valve leaflets.
Mathematical models can provide valuable information to assess and evaluate the mechanical behavior of tissue-engineered constructs. In this study, a structurally based model is applied to describe and analyze the mechanics of tissue-engineered human heart valve leaflets. The results from two orthogonal uniaxial tensile tests are used to determine the model parameters of the constructs after tw...
متن کاملModeling Mitral Valve Leaflets from Three-Dimensional Ultrasound
The geometry of the mitral leaflets, most commonly viewed using three-dimensional ultrasound, is an important input for mechanical models predicting valve closure. Current methods for leaflet modeling from ultrasound either require extensive user interaction, rely on inaccurate assumptions, or produce generic results. The presented method for modeling the mitral leaflets from three-dimensional ...
متن کاملTri-layered elastomeric scaffolds for engineering heart valve leaflets.
Tissue engineered heart valves (TEHVs) that can grow and remodel have the potential to serve as permanent replacements of the current non-viable prosthetic valves particularly for pediatric patients. A major challenge in designing functional TEHVs is to mimic both structural and anisotropic mechanical characteristics of the native valve leaflets. To establish a more biomimetic model of TEHV, we...
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ژورنال
عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery
سال: 2012
ISSN: 0022-5223
DOI: 10.1016/j.jtcvs.2012.01.074